the association of chlamydia pneumonia and helicobacter pylori igg seropositivity with omentin-1, visfatin and adiponectin levels in postmenopausal women
نویسندگان
چکیده
some adipocytokines are cardioprotective or pro-inflammatory for cardiovascular system. chronic infection with chlamydia pneumoniae and helicobacter pylori has been also considered as novel risk factors for atherosclerosis. the main aim of the current population-based study is to investigate the potential link between circulating adipocytokines and chlamydia pneumoniae or helicobacter pylori igg seropositivities. a total of 250 healthy postmenopausal women who participated in a prospective cohort study were evaluated for igg antibodies directed against c.pneumoniae and h. pylori. omentin-1, visfatin, adiponectin, and high sensitivity c-reactive protein were measured by highly specific enzyme-linked immunosorbent assay methods. the prevalence of igg antibodies against c. pneumoniae and h. pylori among the studied population was 20.4% (51 women) and 57.2% (143 women), respectively. there were no significant differences in adipocytokine levels between h. pylori igg seropositive and h. pylori seronegative subjects. similar results for visfatin and omentin-1 were found when c. pneumoniae igg seropositive were compared with c. pneumoniae igg seronegative subjects. however, in general linear model adjusted for age, body mass index and hs-crp levels revealed significant difference between c. pneumoniae seropositive and c. pneumoniae seronegative subjects for circulating adiponectin. in conclusion, chlamydia pneumoniae igg seropositivity was associated with higher adiponectin levels in postmenopausal women. the elucidation of interaction mechanism of chlamydia pneumoniae and a cardioprotective adipocytokine (adiponectin) will be useful in future therapeutic strategies.
منابع مشابه
Omentin-1, visfatin and adiponectin levels in relation to bone mineral density in Iranian postmenopausal women.
The bone and fat interface is implicated in the pathogenesis of postmenopausal osteoporosis. The association between circulating omentin-1 levels and bone mineral density (BMD) in postmenopausal women has never been assessed. A total of 382 healthy postmenopausal women were randomly selected. Omentin-1, visfatin, adiponectin, the receptor activator of nuclear factor-κB ligand (RANKL), osteoprot...
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Pooria A1, Maasoomi M2, Rafiee E3, Rezaee M4, Sabzi F5, Hossain Zadegan H6, Salehi M7, Mozaffari P8 1. Assistant Professor, Department of Surgery, Faculty of Medicine, Lorestan University of Medical Sciences 2. Professor, Department of Surgery, Faculty of Medicine, Kermanshah University of Medical Sciences, 3. Assistant Professor, Faculty of Medicine, Lorestan University of Medical Sciences, D...
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چکیده ندارد.
Strong correlation between Helicobacter pylori seropositivity and Chlamydia pneumoniae IgG concentrations.
Overall, epidemiological studies indicate a weakly positive association between coronary heart disease (CHD) and chronic Helicobacter pylori infection. If H pylori infection increases the incidence of CHD, then it may do so by aVecting some other vascular risk factor(s). If there is a non-causal association between the infection and CHD, then this must be because of some confounding factors. In...
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عنوان ژورنال:
acta medica iranicaجلد ۵۴، شماره ۱۲، صفحات ۷۷۱-۷۷۷
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